[ PRINT ] [ Printing FAQ ] About OncoLink Editorial Board Sponsors Help See Today's OncoTip Usage Statistics Virtual Classroom Abramson Family Cancer Research Institute "Confronting Cancer Through Art" is an exhibition by people whose lives have been touched by cancer. This week we are featuring artwork by: Jacqueline Kniewasser Pontypool, Ontario Visit the Children's Art Gallery This week's artwork was donated by a pediatric cancer patient who received treatment for cancer at The Children's Hospital of Philadelphia.

Ductal Carcinoma in situ Of The Breast: The Breast With Carcinoma in situ Authors: Margaret M. Barnes, M.D Affiliations: Department of Radiation Oncology, University of Pennsylvania Cancer Center Posting Date - March 7, 1997 Last Revision Date: Sunday, 14-Feb-1999 13:54:25 EST Copyright © 1994-1999, The Trustees of the University of Pennsylvania Lobular Carcinoma in situ (LCIS): When the normal lining cells of the lobules begin to grow out of control, the cells will heap up, and under the microscope are seen one or more lobules filled with these abnormal cells: Lobular carcinoma in situ Lobular carcinoma in situ is the least serious breast tissue abnormality, but its presence does place the patient at a higher than normal risk of later developing true breast cancer. The LCIS growth shoyold be removed surgically, and the patient should be followed carefully with mammography and physical breast exams for the rest of her life . Ductal Carcinoma in situ (DCIS): This in situ tumor develops when the lining cells of the breast ducts begin to grow out of control with cells that are pre-malignant. These in situ cancer cells, however, stay inside the basement membrane sleeve of the duct; the tumor does not invade through the basement membrane. Another name for DCIS is intraductal carcinoma of the breast because the carcinoma stays "within" the ducts. Ductal carcinoma in situ and close-up insert of duct cross section The individual cancer cells that are growing in DCIS are believed to be true cancer cells. If untreated, or if treated inappropriately, these cancer cells may eventually develop ability to invade through the basement membrane and become an invasive (or infiltrating) carcinoma with the ultimate ability to spread through the body. Infiltrating ductal carcinoma with duct cross section and metastases through blood and lymph systems Next | Table of Contents | Previous

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